Call Now

WNT Inhibitory Factor 1 (WIF1)

WNT proteins are extracellular signaling molecules involved in the control of embryonic development. This gene encodes a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.The deduced 379-amino acid WIF1 secreted protein contains an N-terminal signal sequence, a 150-amino acid WIF domain, 5 epidermal growth factor (EGF)-like repeats that are similar to those of tenascin, and a C-terminal hydrophilic domain of approximately 45 amino acids. Overexpression of human WIF1 in frog embryos affected somitogenesis depending on the site and timing of WIF1 injection. .

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Hu01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Hu01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Hu01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Hu01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Hu01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Mu01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Mu01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Mu01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Mu01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Mu01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Ra01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Ra01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Ra01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Ra01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Ra01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Ca01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Ca01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Ca01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Ca01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Ca01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Po01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Po01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Po01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Po01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Po01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Bo01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Bo01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Bo01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Bo01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Bo01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Rb01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Rb01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Rb01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Rb01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Rb01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM567Mo01 Recombinant WNT Inhibitory Factor 1 (WIF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM567Mo01 Monoclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IP.
PAM567Mo01 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1) WB; IHC; ICC; IF.
Assay Kits CLM567Mo01 CLIA Kit for WNT Inhibitory Factor 1 (WIF1) CLIA assay for Antigen Detection
ELM567Mo01 ELISA Kit for WNT Inhibitory Factor 1 (WIF1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"A new secreted protein that binds to Wnt proteins and inhibits their activities."
Nature 398:431-436(1999) [PubMed] [Europe PMC] [Abstract]

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Myocilin is a modulator of Wnt signaling."
Mol. Cell. Biol. 29:2139-2154(2009) [PubMed] [Europe PMC] [Abstract]

"NMR structure of the WIF domain of the human Wnt-inhibitory factor-1."
J. Mol. Biol. 357:942-950(2006) [PubMed] [Europe PMC] [Abstract]