Otubain 1 (OTUB1)
HSPC263; OTB1; OTU1; OTU Domain,Ubiquitin Aldehyde Binding 1; Deubiquitinating enzyme OTUB1; Ubiquitin-specific-processing protease OTUB1
Otubain-1 is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains, being specific for lysine48 -linked polyubiquitin but not lysine63 -linked polyubiquitin. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.
The 271-amino acid, 31-kD OTB1 protein contains UB-interaction motifs (UIMs) and UB-associated (UBA) domains, as well as putative nuclear localization signals and a consensus LxxLL motif. RT-PCR and Western blot analyses revealed wide expression of OTB1, with 2 isoforms in leukocytes.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | M555Hu01 | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| PM555Hu01 | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| LM555Hu71 | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| LM555Hu81 | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | M555Mu01 | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| PM555Mu01 | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| LM555Mu71 | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| LM555Mu81 | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | M555Ra01 | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| PM555Ra01 | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Otubain 1 (OTUB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Otubain 1 (OTUB1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Otubain 1 (OTUB1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Otubain 1 (OTUB1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Otubain 1 (OTUB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Otubain 1 (OTUB1) | CLIA assay for Antigen Detection |
Reference
"Otubains: a new family of cysteine proteases in the ubiquitin pathway."
EMBO Rep. 4:517-522(2003) [PubMed] [Europe PMC] [Abstract]
"Two isoforms of otubain 1 regulate T cell anergy via GRAIL."
Nat. Immunol. 5:45-54(2004) [PubMed] [Europe PMC] [Abstract]
"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family."
Chem. Biol. 9:1149-1159(2002) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity."
J. Biol. Chem. 284:16135-16145(2009) [PubMed] [Europe PMC] [Abstract]
"Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1."
J. Mol. Biol. 386:1011-1023(2009) [PubMed] [Europe PMC] [Abstract]
"Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1."
Nature 466:941-946(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
"OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis."
Cell 154:169-184(2013) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Structural basis and specificity of human otubain 1-mediated deubiquitination."
Biochem. J. 418:379-390(2009) [PubMed] [Europe PMC] [Abstract]
"OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function."
Mol. Cell 45:384-397(2012) [PubMed] [Europe PMC] [Abstract]
"The mechanism of OTUB1-mediated inhibition of ubiquitination."
Nature 483:618-622(2012) [PubMed] [Europe PMC] [Abstract]