Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA)
NUCLING
Using a human sequence homologous to the bovine UACA sequence to screen a Jurkat cell cDNA library, they isolated the human homolog, which was found have the same sequence as KIAA1561. Human UACA encodes a deduced 1,449-amino acid protein with a predicted molecular mass of approximately 166 kD. It contains 6 ankyrin repeats, a leucine zipper motif, and coiled-coil domains. The bovine and human proteins share 86% sequence homology. Northern blot analysis demonstrated expression at various levels in all tissues analyzed, with highest expression in skeletal muscle.the prevalence of IgG anti-UACA autoantibodies in patients with panuveitis was significantly higher than that in healthy controls (19.6-28.1% vs 0%, p less than 0.05), indicating that autoimmunity directed against UACA is a common phenomenon in these diseases.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Hu01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Hu01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Hu01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Hu01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Hu01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Mu01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Mu01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Mu01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Mu01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Mu01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Ra01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Ra01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Ra01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Ra01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Ra01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Ca01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Ca01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Ca01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Ca01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Ca01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Po01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Po01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Po01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Po01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Po01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Bo01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Bo01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Bo01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Bo01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Bo01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Rb01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Rb01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Rb01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Rb01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Rb01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM496Mo01 | Recombinant Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM496Mo01 | Monoclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IP. |
| PAM496Mo01 | Polyclonal Antibody to Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM496Mo01 | CLIA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | CLIA assay for Antigen Detection |
| ELM496Mo01 | ELISA Kit for Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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