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Semaphorin 3A (SEMA3A)
Semaphorin 3A (SEMA3A)
SEMAL; Hsema-I; Hsema-III; SEMA1; SEMAD; SEMAIII; SemD; Coll-1; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 3A
SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.The first of the CRMP proteins, CRMP2, was identified as an intracellular messenger required for the growth cone-collapse induced by semaphorin 3A.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
M476Mu02
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
PM476Mu01
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
LM476Mu71
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
M476Ra01
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
MM476Ra21
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
PM476Ra01
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
KEM476Ra
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 3A (SEMA3A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 3A (SEMA3A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 3A (SEMA3A) CLIA assay for Antigen Detection
Reference
"The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules." Cell 75:1389-1399(1993) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed ] [Europe PMC ] [Abstract ]
"SEMA3A deletion in a family with Kallmann syndrome validates the role of semaphorin 3A in human puberty and olfactory system development." Hum. Reprod. 27:1460-1465(2012) [PubMed ] [Europe PMC ] [Abstract ]
"The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma." Nature 469:539-542(2011) [PubMed ] [Europe PMC ] [Abstract ]
"SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome." PLoS Genet. 8:E1002896-E1002896(2012) [PubMed ] [Europe PMC ] [Abstract ]
"The prevalence of CHD7 missense versus truncating mutations is higher in patients with Kallmann syndrome than in typical CHARGE patients." J. Clin. Endocrinol. Metab. 99:E2138-2143(2014) [PubMed ] [Europe PMC ] [Abstract ]
