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Semaphorin 5A (SEMA5A)
Semaphorin 5A (SEMA5A)
SEMAF; SemF; Semaphorin-F; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 5A
SEMA5A belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.
The deduced 1,077-amino acid protein contains an N-terminal signal sequence, followed by a semaphorin domain, 7 thrombospondin type-1 repeats, a putative transmembrane domain, and a short cytoplasmic tail. It also has 13 conserved cysteines and a conserved N-glycosylation site. Northern blot analysis of whole mouse embryos detected 2 Semf transcripts at embryonic day 10, and their expression decreased toward birth.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
M469Hu01
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
MM469Hu21
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
PM469Hu01
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
KEM469Hu
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Semaphorin 5A (SEMA5A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Semaphorin 5A (SEMA5A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Semaphorin 5A (SEMA5A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Semaphorin 5A (SEMA5A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Semaphorin 5A (SEMA5A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Semaphorin 5A (SEMA5A) CLIA assay for Antigen Detection
Reference
"Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval." Biochem. Biophys. Res. Commun. 242:685-691(1998) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Plexin-B3 is a functional receptor for semaphorin 5A." EMBO Rep. 5:710-714(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase." J. Biol. Chem. 285:32436-32445(2010) [PubMed ] [Europe PMC ] [Abstract ]
"Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis." Microvasc. Res. 79:1-9(2010) [PubMed ] [Europe PMC ] [Abstract ]
"Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton." Oncogene 31:595-610(2012) [PubMed ] [Europe PMC ] [Abstract ]
