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Pygopus Homolog 2 (PYGO2)
Pygopus Homolog 2 (PYGO2)
WNT signaling controls many fundamental processes during animal development. WNT transduction is mediated by the association of beta-catenin with nuclear TCF DNA-binding factors. Lgs encodes the homolog of human BCL9, and the authors provided genetic and molecular evidence that these proteins exert their function by physically linking Pygo to beta-cateninThe PYGO1 and PYGO2 proteins, which contain 419 and 406 amino acids, respectively, possess a highly conserved PHD finger that interacts with homology domain-1 (HD1) of BCL9. The findings suggested that the recruitment of PYGO permits beta-catenin to transcriptionally activate WNT target genes and raised the possibility that a deregulation of these events may play a causal role in the development of B-cell malignancies.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
M322Hu01
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
PM322Hu01
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pygopus Homolog 2 (PYGO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pygopus Homolog 2 (PYGO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pygopus Homolog 2 (PYGO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pygopus Homolog 2 (PYGO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pygopus Homolog 2 (PYGO2) CLIA assay for Antigen Detection
Reference
"Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex." Cell 109:47-60(2002) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Large-scale cDNA transfection screening for genes related to cancer development and progression." Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed ] [Europe PMC ] [Abstract ]
"A quantitative atlas of mitotic phosphorylation." Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed ] [Europe PMC ] [Abstract ]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." Anal. Chem. 81:4493-4501(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Sci. Signal. 3:RA3-RA3(2010) [PubMed ] [Europe PMC ] [Abstract ]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Sci. Signal. 4:RS3-RS3(2011) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
