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Serum Deprivation Response Protein (SDPR)

PS-p68; SDR; Cavin-2; Phosphatidylserine Binding Protein

SDPR encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein has also been shown to be a substrate for protein kinase C (PKC) phosphorylation.
The SDPR cDNA encodes a deduced 425-amino acid peptide with a calculated molecular mass of 47.2 kD. The human and mouse proteins share 84% sequence identity; both contain a leucine zipper-like domain with 7 repeats and 2 putative protein kinase C phosphorylation sites. Northern blot analysis of various human tissues showed nearly ubiquitous expression of a 3.1-kb transcript, which was always coexpressed with a shorter transcript. Highest expression was detected in heart and lung.SDPR is able to bind PS liposomes in a calcium-independent manner.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Hu01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Hu01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Hu01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Hu01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Hu01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Mu01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Mu01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Mu01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Mu01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Mu01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Ra01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Ra01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Ra01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Ra01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Ra01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Ca01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Ca01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Ca01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Ca01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Ca01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Po01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Po01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Po01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Po01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Po01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Bo01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Bo01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Bo01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Bo01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Bo01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Rb01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Rb01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Rb01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Rb01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Rb01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM193Mo01 Recombinant Serum Deprivation Response Protein (SDPR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM193Mo01 Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IP.
PAM193Mo01 Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) WB; IHC; ICC; IF.
Assay Kits CLM193Mo01 CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA assay for Antigen Detection
ELM193Mo01 ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein."
Genomics 57:120-129(1999) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].

, Submitted (NOV-2005) to UniProtKB

"Purification and characterization of a major phosphatidylserine-binding phosphoprotein from human platelets."
Biochem. J. 269:729-734(1990) [PubMed] [Europe PMC] [Abstract]

"Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."
J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]

"MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance."
Mol. Cell. Biol. 28:3424-3436(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]