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Testican 1 (TIC1)

SPOCK1; SPOCK; TESTICAN; TIC1; Sparc/Osteonectin,Swcv And Kazal-Like Domains Proteoglycan 1

TIC1 encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.The SPOCK cDNA encodes a deduced 439-amino acid protein with a predicted N-terminal signal sequence and 2 consensus glycosaminoglycan attachment sites. SPOCK, which contains osteonectin-like domains, a Kazal-like sequence, and a cys-trp-cys-val (CWCV) domain, is related to protein families that are involved in adhesion, migration, and cell proliferation.In situ hybridization showed that mouse Spock1 is located predominantly in a subpopulation of pyramidal neurons in the CA3 area of the hippocampus.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Hu01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Hu01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Hu01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Hu01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Hu01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Mu01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Mu01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Mu01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Mu01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Mu01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Ra01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Ra01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Ra01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Ra01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Ra01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Ca01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Ca01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Ca01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Ca01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Ca01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Po01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Po01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Po01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Po01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Po01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Bo01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Bo01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Bo01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Bo01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Bo01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Rb01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Rb01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Rb01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Rb01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Rb01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM121Mo01 Recombinant Testican 1 (TIC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM121Mo01 Monoclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IP.
PAM121Mo01 Polyclonal Antibody to Testican 1 (TIC1) WB; IHC; ICC; IF.
Assay Kits CLM121Mo01 CLIA Kit for Testican 1 (TIC1) CLIA assay for Antigen Detection
ELM121Mo01 ELISA Kit for Testican 1 (TIC1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour."
Eur. J. Biochem. 214:347-350(1993) [PubMed] [Europe PMC] [Abstract]

"Endothelial cell expression of testican mRNA."
Endothelium 5:209-219(1997) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 5."
Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of a human seminal plasma glycosaminoglycan-bearing polypeptide."
Biochem. J. 288:565-569(1992) [PubMed] [Europe PMC] [Abstract]

"LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."
J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]