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Transcription Factor Dp1 (TFDP1)

DP1; DRTF1; DRTF1-polypeptide 1; E2F dimerization partner 1

The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors.
The protein was isolated by virtue of its binding to a DNA sequence taken from the adenovirus E2A promoter. TFDP1 is a component of the DRTF1/E2F transcription factor complex, which coordinates events in the cell cycle by interacting with RB1, the retinoblastoma gene product, and RB-related proteins. DRTF1 activity is downregulated in differentiating embryonal carcinoma cells, and E2F activity is induced in adenovirus-infected HeLa cells.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins M042Hu01 Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
PM042Hu01 Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Transcription Factor Dp1 (TFDP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Transcription Factor Dp1 (TFDP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Transcription Factor Dp1 (TFDP1) CLIA assay for Antigen Detection

Reference

"Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation."
Genes Dev. 7:1850-1861(1993) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 13."
Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein."
EMBO J. 13:3104-3114(1994) [PubMed] [Europe PMC] [Abstract]

"In vivo association of E2F and DP family proteins."
Mol. Cell. Biol. 15:2536-2546(1995) [PubMed] [Europe PMC] [Abstract]

"A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells."
Science 296:1132-1136(2002) [PubMed] [Europe PMC] [Abstract]

"Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence."
Mol. Cell 26:539-551(2007) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes."
Mol. Cell. Biol. 30:2293-2304(2010) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]