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Tolloid Like Protein 1 (TLL1)
Tolloid Like Protein 1 (TLL1)
TLL1 encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. A similar protein in mice is required during heart development and specifically processes procollagen C-propeptides and chordin at similar cleavage sites. As previously demonstrated for BMP1 and TLD, TLL1 specifically processes procollagen C-propeptides at the physiologically relevant site, whereas TLL2 lacks this activity. BMP1 and TLL1 cleave chordin, at sites similar to procollagen C-propeptide cleavage sites, and counteract dorsalizing effects of chordin upon overexpression on Xenopus embryos. Proteases TLD and TLL2 do not cleave chordin.TLL1 gene plays multiple roles in formation of the mammalian heart and is essential for formation of the interventricular septum.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
M024Hu01
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
MM024Hu21
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
PM024Hu01
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
KEM024Hu
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Tolloid Like Protein 1 (TLL1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Tolloid Like Protein 1 (TLL1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Tolloid Like Protein 1 (TLL1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Tolloid Like Protein 1 (TLL1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Tolloid Like Protein 1 (TLL1) CLIA assay for Antigen Detection
Reference
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis." Dev. Biol. 213:283-300(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Bone morphogenetic protein-1 processes probiglycan." J. Biol. Chem. 275:30504-30511(2000) [PubMed ] [Europe PMC ] [Abstract ]
"Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures." J. Biol. Chem. 276:22537-22543(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases." J. Mol. Biol. 384:228-239(2008) [PubMed ] [Europe PMC ] [Abstract ]
"The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Mutations in mammalian tolloid-like 1 gene detected in adult patients with ASD." Eur. J. Hum. Genet. 17:344-351(2009) [PubMed ] [Europe PMC ] [Abstract ]
