Histone Cluster 2, H2be (HIST2H2BE)

H2BFQ; H2B/q; H2B.1; H2B Histone Family Member Q

SPN	K074
HGNC	4760
MGI	2448415
PubMed	1469070
RGD	1562346
UniProt	Q16778
Wiki	HIST2H2BE

HIST2H2BE encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

This intronless gene encodes a polypeptide of 126 amino acids. This H2B gene is paired with a functional H2A histone gene, and the 2 genes are separated by a bidirectionally transcribed intergenic promoter region of 329 nucleotides containing consensus TATA and CCAAT boxes and an OTF-1 element. The 3-prime untranslated region of the H2B.1 gene contains the conserved histone 3-prime stem-loop motif commonly found in cell cycle-dependent histone genes, as well as a polyadenylation signal typical of constitutively expressed histone genes.

Reference

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