Histone Cluster 1, H2ac (HIST1H2AC)

H2AFL; H2A Histone Family Member L

SPN	K063
HGNC	4733
MGI	2448287
PubMed	12408966
RGD	1597155
UniProt	Q93077
Wiki	HIST1H2AC

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.

HIST1H2AC is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Reference

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