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Dihydrodiol Dehydrogenase 2 (DDH2)

AKR1C2; DD; BABP; DD2; HAKRD; MCDR2; Aldo-Keto Reductase Family 1,Member C2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase Type III

Dihydrodiol dehydrogenase (DD; EC 1.3.1.20), a member of the aldo-oxo reductase (AKR) superfamily, catalyzes the NADP-linked oxidation of trans-dihydrodiols of aromatic hydrocarbons to corresponding catechols. DDH2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins J806Hu01 Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies MJ806Hu21 Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
PJ806Hu01 Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits KEJ806Hu ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dihydrodiol Dehydrogenase 2 (DDH2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dihydrodiol Dehydrogenase 2 (DDH2) Bioactivity
Antibodies NONE Monoclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dihydrodiol Dehydrogenase 2 (DDH2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dihydrodiol Dehydrogenase 2 (DDH2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dihydrodiol Dehydrogenase 2 (DDH2) CLIA assay for Antigen Detection

Reference

"Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase."
J. Steroid Biochem. Mol. Biol. 46:673-679(1993) [PubMed] [Europe PMC] [Abstract]

"cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase."
Biochim. Biophys. Acta 1186:129-132(1994) [PubMed] [Europe PMC] [Abstract]

"Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein."
Gene 149:357-361(1994) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning of human type 3 3 alpha-hydroxysteroid dehydrogenase that differs from 20 alpha-hydroxysteroid dehydrogenase by seven amino acids."
Biochem. Biophys. Res. Commun. 228:474-479(1996) [PubMed] [Europe PMC] [Abstract]

"Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA."
Biochem. J. 334:399-405(1998) [PubMed] [Europe PMC] [Abstract]

"Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes."
Genes Cells 5:111-125(2000) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells."
Biochem. J. 313:373-376(1996) [PubMed] [Europe PMC] [Abstract]

"cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family."
J. Biol. Chem. 268:10448-10457(1993) [PubMed] [Europe PMC] [Abstract]

"Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation."
Am. J. Hum. Genet. 89:201-218(2011) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate."
Biochemistry 40:10161-10168(2001) [PubMed] [Europe PMC] [Abstract]

"Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution."
J. Biol. Chem. 276:42091-42098(2001) [PubMed] [Europe PMC] [Abstract]

"Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an 'induced-fit' mechanism and a conserved basic motif involved in the binding of androgen."
Protein Sci. 14:1485-1497(2005) [PubMed] [Europe PMC] [Abstract]

"Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme."
J. Mol. Biol. 364:747-763(2006) [PubMed] [Europe PMC] [Abstract]

"Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding."
J. Mol. Biol. 369:525-540(2007) [PubMed] [Europe PMC] [Abstract]