Claudin 6 (CLDN6)
Skullin
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.
CLDN6 encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Hu01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Hu01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Hu01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Hu01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Hu01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Mu01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Mu01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Mu01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Mu01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Mu01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Ra01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Ra01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Ra01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Ra01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Ra01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Ca01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Ca01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Ca01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Ca01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Ca01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Po01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Po01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Po01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Po01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Po01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Bo01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Bo01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Bo01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Bo01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Bo01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Rb01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Rb01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Rb01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Rb01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Rb01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ692Mo01 | Recombinant Claudin 6 (CLDN6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ692Mo01 | Monoclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IP. |
| PAJ692Mo01 | Polyclonal Antibody to Claudin 6 (CLDN6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ692Mo01 | CLIA Kit for Claudin 6 (CLDN6) | CLIA assay for Antigen Detection |
| ELJ692Mo01 | ELISA Kit for Claudin 6 (CLDN6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus."
J. Virol. 81:12465-12471(2007) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]