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Peptidase Inhibitor 16 (PI16)

MSMBBP; CRISP9; PSPBP; Microseminoprotein, Beta-Binding Protein; Protease Inhibitor 16; PSP94-binding protein; Cysteine-rich secretory protein 9

PI16 is a putative serine protease inhibitor. PI16 may serve as a marker following prostatectomy for prostate cancer. This protein binds with high affinity to PSP94.
PI16 expression is enhanced after serum stimulation of primary cardiomyocytes and is rapidly secreted into the conditioned medium of cardiomyocytes. PI16 is overexpressed in the hypertrophic and failing heart and inhibits cardiomyocyte growth. Suppression of endogenous PI16 expression in primary cardiomyocytes significantly enhances cardiomyocyte size. Transgenic mice overexpressing PI16 in a cardiomyocyte-specific manner show normal cardiac function but have smaller hearts with hypotrophic cardiomyocytes.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Hu01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Hu01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Hu01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Hu01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Hu01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Mu01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Mu01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Mu01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Mu01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Mu01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Ra01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Ra01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Ra01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Ra01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Ra01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Ca01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Ca01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Ca01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Ca01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Ca01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Po01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Po01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Po01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Po01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Po01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Bo01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Bo01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Bo01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Bo01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Bo01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Rb01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Rb01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Rb01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Rb01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Rb01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI336Mo01 Recombinant Peptidase Inhibitor 16 (PI16) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI336Mo01 Monoclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IP.
PAI336Mo01 Polyclonal Antibody to Peptidase Inhibitor 16 (PI16) WB; IHC; ICC; IF.
Assay Kits CLI336Mo01 CLIA Kit for Peptidase Inhibitor 16 (PI16) CLIA assay for Antigen Detection
ELI336Mo01 ELISA Kit for Peptidase Inhibitor 16 (PI16) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"Identification, purification and characterization of a novel human blood protein with binding affinity for prostate secretory protein of 94 amino acids."
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"Prognostic value of prostate secretory protein of 94 amino acids and its binding protein after radical prostatectomy."
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Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract]