Home
›
Reprimo (RPRM)
Reprimo (RPRM)
Candidate Mediator Of The p53 Dependent G2 Arrest
RPRM is induced following x-irradiation in a p53-dependent manner and is a downstream mediator of p53 action. Overexpression of RPRM in HeLa cells by transfection resulted in G2 arrest of the cell cycle by inhibiting both CDC2 activity and nuclear translocation of the CDC2-cyclin B1 (CCNB1) complex.Using a differential display screening approach on mouse embryonal fibroblasts to identify genes that are induced by p53 following x-irradiation, Ohki et al. (2000) identified one, which they termed Reprimo, that is involved in cell cycle regulation. Ohki et al. (2000) cloned mouse and human Reprimo cDNAs, which encode deduced 109-amino acid proteins sharing 98% sequence identity. The Reprimo protein is N-glycosylated and localizes to the cytoplasm.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
PG079Hu01
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
G079Ra01
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
PG079Ra01
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
LG079Ra71
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
LG079Ra81
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Reprimo (RPRM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Reprimo (RPRM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Reprimo (RPRM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Reprimo (RPRM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Reprimo (RPRM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Reprimo (RPRM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Reprimo (RPRM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Reprimo (RPRM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Reprimo (RPRM) CLIA assay for Antigen Detection
Reference
"Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase." J. Biol. Chem. 275:22627-22630(2000) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed ] [Europe PMC ] [Abstract ]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
