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Insulin Like Growth Factor 2 (IGF2)

INSIGF; IGF-II; Somatomedin A; Preptin; Insulin-like growth factor II Ala-25 Del

IGF2 is a regulatory peptide (IGF-II) critical for normal fetal growth. It has been shown to be implicated in tumor progression in a variety of human neoplasms, eg, Wilms' tumors and rhabdomyosarcomas.

IGF2 transcription is controlled by four distinct promoters, P1 to P4, of which promoters P2, P3, and P4 are epigenetically regulated by genomic imprinting. The IGF-II protein can bind to different receptors: the IGF-I receptor (IGF-IR) has classically been regarded as the major mediator of its proliferative effect; the insulin receptor (IR), especially its isoform A (IR-A), which resembles the IGF-IR in its effect; and the IGF-II receptor (IGF-IIR), which internalizes IGF-II into the cell, thereby regulating its extracellular concentration, and eventually leading to its lysosomal degradation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Hu01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Hu01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Hu01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Hu01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Hu01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Mu01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Mu01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Mu01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Mu01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Mu01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Ra01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Ra01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Ra01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Ra01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Ra01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Ca01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Ca01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Ca01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Ca01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Ca01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Po01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Po01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Po01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Po01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Po01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Bo01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Bo01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Bo01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Bo01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Bo01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Rb01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Rb01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Rb01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Rb01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Rb01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW656Mo01 Recombinant Insulin Like Growth Factor 2 (IGF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW656Mo01 Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IP.
PAW656Mo01 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2) WB; IHC; ICC; IF.
Assay Kits CLW656Mo01 CLIA Kit for Insulin Like Growth Factor 2 (IGF2) CLIA assay for Antigen Detection
ELW656Mo01 ELISA Kit for Insulin Like Growth Factor 2 (IGF2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"Preptin, another peptide product of the pancreatic beta-cell, is osteogenic in vitro and in vivo."
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