Substance P (SP)
| SPN | W410 |
| PubMed | 16585438 |
| Wiki | Substance_P |
In the field of neuroscience, substance P (SP) is a neuropeptide: an undecapeptide that functions as a neurotransmitter and as a neuromodulator. It belongs to the tachykinin neuropeptide family. Substance P and its closely related neuropeptide neurokinin A (NKA) are produced from a polyprotein precursor after differential splicing of the preprotachykinin A gene. The deduced amino acid sequence of substance P is as follows:Arg Pro Lys Pro Gln Gln Phe Phe Gly Leu Met
Substance P is released from the terminals of specific sensory nerves, it is found in the brain and spinal cord, and is associated with inflammatory processes and pain.Substance P was originally discovered in 1931 by Ulf von Euler and John H. Gaddum as a tissue extract that caused intestinal contraction in vitro. Its tissue distribution and biologic actions were further investigated over the following decades.
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | N/A | Recombinant Substance P (SP) | Antigenic Transformation Customized Service Offer |
| Antibodies | N/A | Monoclonal Antibody to Substance P (SP) | Monoclonal Antibody Customized Service Offer |
| N/A | Polyclonal Antibody to Substance P (SP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | N/A | CLIA Kit for Substance P (SP) | CLIA Kit Customized Service Offer |
| N/A | ELISA Kit for Substance P (SP) | ELISA Kit Customized Service Offer |