Coagulation Factor X (F10)
FX; FXA; Stuart Prower Factor; Thrombokinase
As the only known physiological activator of thrombin, factor X is a vitamin K-dependent plasma protease that plays a pivotal role in blood coagulation. Human factor X is initially synthesized in the liver as a single-chain precursor of 488 amino acid residues with a signal peptide and a pro region (residues 1 - 40). Both the intrinsic and extrinsic pathways activate factor X to Xa, which consists of light (residues 41 - 179) and heavy (residues 235 - 488) chains linked by a disulfide bond. The light chain contains a Gla and two EGF-like domains and the heavy chain corresponds to the serine protease domain. The full-length human factor X was expressed and the pro enzyme was purified and activated. The active protease was further purified and analyzed for its activity towards either peptides or proteins containing a Xa cleavage site.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Hu01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Hu01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Hu01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Hu01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Hu01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Mu01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Mu01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Mu01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Mu01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Mu01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Ra01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Ra01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Ra01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Ra01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Ra01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Ca01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Ca01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Ca01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Ca01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Ca01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Po01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Po01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Po01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Po01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Po01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Bo01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Bo01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Bo01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Bo01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Bo01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Rb01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Rb01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Rb01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Rb01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Rb01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV977Mo01 | Recombinant Coagulation Factor X (F10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV977Mo01 | Monoclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IP. |
| PAV977Mo01 | Polyclonal Antibody to Coagulation Factor X (F10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV977Mo01 | CLIA Kit for Coagulation Factor X (F10) | CLIA assay for Antigen Detection |
| ELV977Mo01 | ELISA Kit for Coagulation Factor X (F10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Erratum
Nat. Genet. 23:373-373(1999)
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Biochemistry 53:6992-7001(2014) [PubMed] [Europe PMC] [Abstract]