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Fibrinogen Alpha (FGa)

Fib2; FG-A; Fibrinopeptide A

Fibrinogen alpha chain is the alpha component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots.

In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Hu01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Hu01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Hu01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Hu01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Hu01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Mu01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Mu01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Mu01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Mu01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Mu01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Ra01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Ra01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Ra01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Ra01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Ra01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Ca01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Ca01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Ca01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Ca01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Ca01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Po01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Po01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Po01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Po01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Po01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Bo01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Bo01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Bo01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Bo01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Bo01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Rb01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Rb01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Rb01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Rb01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Rb01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV668Mo01 Recombinant Fibrinogen Alpha (FGa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV668Mo01 Monoclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IP.
PAV668Mo01 Polyclonal Antibody to Fibrinogen Alpha (FGa) WB; IHC; ICC; IF.
Assay Kits CLV668Mo01 CLIA Kit for Fibrinogen Alpha (FGa) CLIA assay for Antigen Detection
ELV668Mo01 ELISA Kit for Fibrinogen Alpha (FGa) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"Glycoproteomic analysis of human fibrinogen reveals novel regions of O-glycosylation."
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Erratum
Nat. Genet. 23:373-373(1999)

"The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance."
Br. J. Haematol. 134:220-226(2006) [PubMed] [Europe PMC] [Abstract]

"Clinical and molecular characterisation of 21 patients affected by quantitative fibrinogen deficiency."
Thromb. Haemost. 113:567-576(2015) [PubMed] [Europe PMC] [Abstract]