Acylation Stimulating Protein (ASP)
Acyl Stimulation Protein
Acylation Stimulating Protein (ASP) is one of the factors that control adipose tissue function. It was initially identified from human plasma, and determined to be a derivative of the 3rd complement component (C3). Arginine removal from activated C3 (C3a) by carboxypeptidase results in C3a-desArg, also known as ASP.
Human fat cells have been shown to have mRNA for Adipsin (complement factor D), C3 and factor B, all of which are components necessary to generate C3a, the precursor for ASP. Basal production of ASP in adipocytes is dependent on adipocyte differentiation, with ASP production increasing after 7 days of adipocyte differentiation. While ASP is produced by the interaction of C3, factor B and Adipsin in the alternate complement pathway, it can also be potentially generated by the classical complement pathway as well as the lectin pathway.
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | N/A | Recombinant Acylation Stimulating Protein (ASP) | Antigenic Transformation Customized Service Offer |
| Antibodies | N/A | Monoclonal Antibody to Acylation Stimulating Protein (ASP) | Monoclonal Antibody Customized Service Offer |
| N/A | Polyclonal Antibody to Acylation Stimulating Protein (ASP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | N/A | CLIA Kit for Acylation Stimulating Protein (ASP) | CLIA Kit Customized Service Offer |
| N/A | ELISA Kit for Acylation Stimulating Protein (ASP) | ELISA Kit Customized Service Offer |