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Cytovillin (CVL)

EZR; Ezrin; VIL2; CVIL; CVL; Villin 2; p81

Cytovillin is a microvillar cytoplasmic peripheral membrane protein, with prominent expression in vivo in placental syncytiotrophoblasts and certain human tumors. Cytovillin cDNA was cloned from a human placental lambda gt11 library using affinity purified antibodies.

The identity of cytovillin cDNA clones was confirmed by expression of cytovillin in Escherichia coli and using antibodies raised against the expressed fusion protein in comparison with antibodies against cytovillin purified from cultured human choriocarcinoma cells. In these cells Northern blotting analysis identified a major 3.5-kilobase cytovillin mRNA. The cDNA encodes a protein of 575 amino acids corresponding to a molecular weight of 68,084.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Hu01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Hu01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Hu01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Hu01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Hu01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Mu01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Mu01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Mu01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Mu01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Mu01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Ra01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Ra01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Ra01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Ra01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Ra01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Ca01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Ca01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Ca01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Ca01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Ca01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Po01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Po01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Po01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Po01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Po01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Bo01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Bo01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Bo01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Bo01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Bo01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Rb01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Rb01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Rb01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Rb01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Rb01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV535Mo01 Recombinant Cytovillin (CVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV535Mo01 Monoclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IP.
PAV535Mo01 Polyclonal Antibody to Cytovillin (CVL) WB; IHC; ICC; IF.
Assay Kits CLV535Mo01 CLIA Kit for Cytovillin (CVL) CLIA assay for Antigen Detection
ELV535Mo01 ELISA Kit for Cytovillin (CVL) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1."
EMBO J. 8:4133-4142(1989) [PubMed] [Europe PMC] [Abstract]

"Cytovillin, a microvillar Mr 75,000 protein. cDNA sequence, prokaryotic expression, and chromosomal localization."
J. Biol. Chem. 264:16727-16732(1989) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes."
Biochem. Biophys. Res. Commun. 224:666-674(1996) [PubMed] [Europe PMC] [Abstract]