Dystrophin (DMD)
CMD3B; Muscular Dystrophy,Duchenne And Becker Types
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Hu01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Hu01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Hu01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Hu01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Hu01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Mu01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Mu01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Mu01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Mu01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Mu01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Ra01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Ra01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Ra01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Ra01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Ra01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Ca01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Ca01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Ca01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Ca01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Ca01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Po01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Po01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Po01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Po01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Po01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Bo01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Bo01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Bo01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Bo01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Bo01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Rb01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Rb01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Rb01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Rb01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Rb01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV331Mo01 | Recombinant Dystrophin (DMD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV331Mo01 | Monoclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IP. |
| PAV331Mo01 | Polyclonal Antibody to Dystrophin (DMD) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV331Mo01 | CLIA Kit for Dystrophin (DMD) | CLIA assay for Antigen Detection |
| ELV331Mo01 | ELISA Kit for Dystrophin (DMD) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein."
Cell 53:219-228(1988) [PubMed] [Europe PMC] [Abstract]
"Two human cDNA molecules coding for the Duchenne muscular dystrophy (DMD) locus are highly homologous."
Nucleic Acids Res. 17:5391-5391(1989) [PubMed] [Europe PMC] [Abstract]
"A 71-kilodalton protein is a major product of the Duchenne muscular dystrophy gene in brain and other nonmuscle tissues."
Proc. Natl. Acad. Sci. U.S.A. 89:5346-5350(1992) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals."
Cell 50:509-517(1987) [PubMed] [Europe PMC] [Abstract]
"Alternative splicing of human dystrophin mRNA generates isoforms at the carboxy terminus."
Nature 338:509-511(1989) [PubMed] [Europe PMC] [Abstract]
"Deletions of fetal and adult muscle cDNA in Duchenne and Becker muscular dystrophy patients."
EMBO J. 6:3277-3283(1987) [PubMed] [Europe PMC] [Abstract]
"Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification."
Nucleic Acids Res. 16:11141-11156(1988) [PubMed] [Europe PMC] [Abstract]
"High resolution deletion breakpoint mapping in the DMD gene by whole cosmid hybridization."
Nucleic Acids Res. 17:5611-5621(1989) [PubMed] [Europe PMC] [Abstract]
"Cloning and characterization of alternatively spliced isoforms of Dp71."
Hum. Mol. Genet. 4:1475-1483(1995) [PubMed] [Europe PMC] [Abstract]
"Detailed analysis of the repeat domain of dystrophin reveals four potential hinge segments that may confer flexibility."
J. Biol. Chem. 265:4560-4566(1990) [PubMed] [Europe PMC] [Abstract]
"Identification and characterization of the dystrophin anchoring site on beta-dystroglycan."
J. Biol. Chem. 270:27305-27310(1995) [PubMed] [Europe PMC] [Abstract]
"Syntrophin binds to an alternatively spliced exon of dystrophin."
J. Cell Biol. 128:363-371(1995) [PubMed] [Europe PMC] [Abstract]
"The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives."
J. Biol. Chem. 271:2724-2730(1996) [PubMed] [Europe PMC] [Abstract]
"A splice variant of Dp71 lacking the syntrophin binding site is expressed in early stages of human neural development."
Brain Res. Dev. Brain Res. 103:77-82(1997) [PubMed] [Europe PMC] [Abstract]
"Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells."
J. Biol. Chem. 275:15851-15860(2000) [PubMed] [Europe PMC] [Abstract]
"Expression and synthesis of alternatively spliced variants of Dp71 in adult human brain."
Neuromuscul. Disord. 10:187-193(2000) [PubMed] [Europe PMC] [Abstract]
"The interaction of dystrophin with beta-dystroglycan is regulated by tyrosine phosphorylation."
Cell. Signal. 13:625-632(2001) [PubMed] [Europe PMC] [Abstract]
"Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19."
Mol. Biol. Cell 16:4280-4293(2005) [PubMed] [Europe PMC] [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
"Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue."
Cell. Mol. Life Sci. 63:1614-1631(2006) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan."
Nat. Struct. Biol. 7:634-638(2000) [PubMed] [Europe PMC] [Abstract]
"The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy."
Structure 8:481-491(2000) [PubMed] [Europe PMC] [Abstract]
"Searching for the 1 in 2,400,000: a review of dystrophin gene point mutations."
Hum. Mutat. 4:1-11(1994) [PubMed] [Europe PMC] [Abstract]
"Microlesions and polymorphisms in the Duchenne/Becker muscular dystrophy gene."
Hum. Genet. 94:111-116(1994) [PubMed] [Europe PMC] [Abstract]
"A missense mutation in the dystrophin gene in a Duchenne muscular dystrophy patient."
Nat. Genet. 4:357-360(1993) [PubMed] [Europe PMC] [Abstract]
"Identification of a missense mutation, single base deletion and a polymorphism in the dystrophin exon 16."
Hum. Mol. Genet. 3:1173-1174(1994) [PubMed] [Europe PMC] [Abstract]
"Novel small mutations along the DMD/BMD gene associated with different phenotypes."
Hum. Mol. Genet. 3:1907-1908(1994) [PubMed] [Europe PMC] [Abstract]
"A cysteine 3340 substitution in the dystroglycan-binding domain of dystrophin associated with Duchenne muscular dystrophy, mental retardation and absence of the ERG b-wave."
Hum. Mol. Genet. 5:973-975(1996) [PubMed] [Europe PMC] [Abstract]
"Evidence for a dystrophin missense mutation as a cause of X-linked dilated cardiomyopathy."
Circulation 95:2434-2440(1997) [PubMed] [Europe PMC] [Abstract]
"A dystrophin missense mutation showing persistence of dystrophin and dystrophin-associated proteins yet a severe phenotype."
Ann. Neurol. 44:971-976(1998) [PubMed] [Europe PMC] [Abstract]
"Identification of point mutations in Turkish DMD/BMD families using multiplex-single stranded conformation analysis (SSCA)."
Eur. J. Hum. Genet. 7:765-770(1999) [PubMed] [Europe PMC] [Abstract]
"Comprehensive mutation scanning of the dystrophin gene in patients with nonsyndromic X-linked dilated cardiomyopathy."
J. Am. Coll. Cardiol. 40:1120-1124(2002) [PubMed] [Europe PMC] [Abstract]
"Mutations in the dystrophin gene are associated with sporadic dilated cardiomyopathy."
Mol. Genet. Metab. 77:119-126(2002) [PubMed] [Europe PMC] [Abstract]
"Rapid direct sequence analysis of the dystrophin gene."
Am. J. Hum. Genet. 72:931-939(2003) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
"Clinical and molecular characterization of a cohort of patients with novel nucleotide alterations of the Dystrophin gene detected by direct sequencing."
BMC Med. Genet. 12:37-37(2011) [PubMed] [Europe PMC] [Abstract]
"The ZZ domain of dystrophin in DMD: making sense of missense mutations."
Hum. Mutat. 35:257-264(2014) [PubMed] [Europe PMC] [Abstract]
"Missense mutation Lys18Asn in dystrophin that triggers X-linked dilated cardiomyopathy decreases protein stability, increases protein unfolding, and perturbs protein structure, but does not affect protein function."
PLoS ONE 9:E110439-E110439(2014) [PubMed] [Europe PMC] [Abstract]