Myosin Heavy Chain 14, Non Muscle (MYH14)
DFNA4; NMHC-II-C; MHC16; MYH17
- Myosin-14 is a member of the myosin superfamily. Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. Expression was also detected in brain, heart, colon, kidney, liver, small intestine, and lung, but not in thymus, spleen, placenta, and lymphocytes. RNA dot blot analysis detected elevated MYH14 expression in corpus callosum. Little MYH14 was detected in organs composed mainly of smooth muscle, such as aorta, uterus, and bladder. Human fetal tissues showed little or no MYH14 expression compared with adult tissues.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Hu01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Hu01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Hu01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Hu01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Hu01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Mu01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Mu01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Mu01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Mu01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Mu01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Ra01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Ra01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Ra01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Ra01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Ra01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Ca01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Ca01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Ca01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Ca01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Ca01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Po01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Po01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Po01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Po01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Po01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Bo01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Bo01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Bo01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Bo01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Bo01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Rb01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Rb01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Rb01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Rb01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Rb01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT328Mo01 | Recombinant Myosin Heavy Chain 14, Non Muscle (MYH14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT328Mo01 | Monoclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IP. |
| PAT328Mo01 | Polyclonal Antibody to Myosin Heavy Chain 14, Non Muscle (MYH14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT328Mo01 | CLIA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | CLIA assay for Antigen Detection |
| ELT328Mo01 | ELISA Kit for Myosin Heavy Chain 14, Non Muscle (MYH14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
, Submitted (NOV-2006) to UniProtKB
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"Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4)."
Am. J. Hum. Genet. 74:770-776(2004) [PubMed] [Europe PMC] [Abstract]
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Am. J. Med. Genet. A 139:9-12(2005) [PubMed] [Europe PMC] [Abstract]
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Hum. Mutat. 32:669-677(2011) [PubMed] [Europe PMC] [Abstract]