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Tubulin Beta 6 (TUBb6)

Tubulin Beta 6 belongs to the tubulin family.Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Hu01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Hu01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Hu01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Hu01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Hu01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Mu01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Mu01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Mu01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Mu01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Mu01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Ra01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Ra01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Ra01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Ra01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Ra01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Ca01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Ca01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Ca01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Ca01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Ca01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Po01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Po01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Po01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Po01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Po01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Bo01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Bo01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Bo01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Bo01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Bo01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Rb01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Rb01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Rb01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Rb01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Rb01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS090Mo01 Recombinant Tubulin Beta 6 (TUBb6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS090Mo01 Monoclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IP.
PAS090Mo01 Polyclonal Antibody to Tubulin Beta 6 (TUBb6) WB; IHC; ICC; IF.
Assay Kits CLS090Mo01 CLIA Kit for Tubulin Beta 6 (TUBb6) CLIA assay for Antigen Detection
ELS090Mo01 ELISA Kit for Tubulin Beta 6 (TUBb6) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation."
Cell 137:1076-1087(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Tumoral and tissue-specific expression of the major human beta-tubulin isotypes."
Cytoskeleton 67:214-223(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]