Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1)

NAP1; NAP1L; NRP; NAP-1-related protein

SPN	P165
HGNC	7637
MGI	1855693
PubMed	9730615
RGD	71094
UniProt	P55209
Wiki	NAP1L1

NAP1L1encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. Alternative splicing of this gene results in several transcript variants; however, not all have been fully described.

The deduced amino acid sequence of the identified protein, designated NRP (for 'NAP-related protein'), has a potential 7-residue nuclear localization motif, 3 clusters of highly acidic residues, and other structural features found in various proteins implicated in chromatin formation. NRP transcript was detected in all human tissues and cell lines studied, but levels were somewhat increased in rapidly proliferating cells.

Reference

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