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CutC Copper Transporter (CUTC)

CGI-32; Copper homeostasis protein cutC homolog

Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper. Li et al. (2005) cloned a member of the CUT gene family, CUTC, from a human fetal brain cDNA library. CUTC encodes a deduced 273-amino acid protein with a molecular mass of about 29.3 kD. The CUTC protein shares 89% and 44% sequence identity with the mouse and E. coli CutC proteins, respectively. RT-PCR analysis revealed expression of CUTC in all human tissues examined, with lowest expression in skeletal muscle, pancreas, prostate, and small intestine. Expression of a CUTC-pEGF fusion plasmid in COS-7 and AD293 cells demonstrated the presence of CUTC in the cytoplasm of both cell types and in the nucleus of AD293 cells.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Hu01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Hu01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Hu01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Hu01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Hu01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Mu01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Mu01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Mu01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Mu01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Mu01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Ra01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Ra01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Ra01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Ra01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Ra01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Ca01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Ca01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Ca01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Ca01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Ca01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Po01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Po01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Po01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Po01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Po01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Bo01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Bo01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Bo01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Bo01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Bo01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Rb01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Rb01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Rb01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Rb01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Rb01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM996Mo01 Recombinant CutC Copper Transporter (CUTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM996Mo01 Monoclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IP.
PAM996Mo01 Polyclonal Antibody to CutC Copper Transporter (CUTC) WB; IHC; ICC; IF.
Assay Kits CLM996Mo01 CLIA Kit for CutC Copper Transporter (CUTC) CLIA assay for Antigen Detection
ELM996Mo01 ELISA Kit for CutC Copper Transporter (CUTC) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification and characterization of a novel Cut family cDNA that encodes human copper transporter protein CutC."
Biochem. Biophys. Res. Commun. 337:179-183(2005) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human copper homeostasis protein CutC reveals a potential copper-binding site."
J. Struct. Biol. 169:399-405(2010) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]