Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)

MP-3; IMP3; KOC1; VICKZ3; CT98; IGF II mRNA Binding Protein 3; Cancer/Testis Antigen 98; KH domain-containing protein overexpressed in cancer

SPN	M770
HGNC	28868
MGI	1890359
PubMed	22840368
RGD	1306512
UniProt	O00425
Wiki	IGF2BP3

IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level).

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Hu01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Hu01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Hu01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Hu01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Hu01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Mu01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Mu01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Mu01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Mu01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Mu01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Ra01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Ra01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Ra01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Ra01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Ra01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Ca01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Ca01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Ca01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Ca01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Ca01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Po01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Po01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Po01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Po01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Po01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Bo01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Bo01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Bo01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Bo01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Bo01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Rb01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Rb01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Rb01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Rb01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Rb01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPM770Mo01	Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAM770Mo01	Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IP.
Antibodies	PAM770Mo01	Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	WB; IHC; ICC; IF.
Assay Kits	CLM770Mo01	CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	CLIA assay for Antigen Detection
Assay Kits	ELM770Mo01	ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"Solution structure of RNA binding domain in insulin-like growth factor 2 mRNA-binding protein 3."
Submitted (JUN-2007) to the PDB data bank