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Actue Renal Failure (ARF)

Kidney failure; Renal insufficiency

Renal failure is a medical condition of impaired kidney function in which the kidneys fail to adequately filter metabolic wastes from the blood. The two main forms are acute kidney injury, which is often reversible with adequate treatment, and chronic kidney disease, which is often not reversible. Acute kidney injury, previously called acute renal failure (ARF), is an abrupt loss of kidney function that develops within 7 days. Renal failure is mainly determined by a decrease in glomerular filtration rate, which is the rate at which blood is filtered in the glomeruli of the kidney. Studies showed that atrial natriuretic peptide (ANP) has been shown to reverse experimental models of ischemic acute renal failure.