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Malate Dehydrogenase 1 (MDH1)

MDHA; Malate Dehydrogenase 1,NAD(Soluble); Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase

Malate dehydrogenase (EC 1.1.1.37) (MDH) is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of malate to pyruvate producing NADPH.
Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. In order to get the oxaloacetate out of the mitochondria, malate dehydrogenase reduces it to malate, and it then traverses the inner mitochondrial membrane.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins P062Hu01 Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies MP062Hu21 Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
PP062Hu01 Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits KEP062Hu ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins P062Ra01 Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies MP062Ra21 Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
PP062Ra01 Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits KEP062Ra ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Malate Dehydrogenase 1 (MDH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Malate Dehydrogenase 1 (MDH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Malate Dehydrogenase 1 (MDH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Malate Dehydrogenase 1 (MDH1) CLIA assay for Antigen Detection

Reference

"Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1)."
Genomics 32:128-130(1996) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

, Submitted (MAY-2006) to UniProtKB

"The human myocardial two-dimensional gel protein database: update 1994."
Electrophoresis 15:1459-1465(1994) [PubMed] [Europe PMC] [Abstract]

, Submitted (MAR-2007) to UniProtKB

"Biochemical and genetic identity of alpha-keto acid reductase and cytoplasmic malate dehydrogenase from human erythrocytes."
Ann. Hum. Genet. 52:25-37(1988) [PubMed] [Europe PMC] [Abstract]

"Proteomic identification of proteins conjugated to ISG15 in mouse and human cells."
Biochem. Biophys. Res. Commun. 336:496-506(2005) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity."
J. Lipid Res. 53:1864-1876(2012) [PubMed] [Europe PMC] [Abstract]

"Resveratrol-induced changes of the human adipocyte secretion profile."
J. Proteome Res. 11:4733-4743(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]