Insulin Like Growth Factor 1 (IGF1)
IGFI; IGF1A; IBP1; MGF; Somatomedin C; Mechano Growth Gactor
Insulin-like Growth Factor I is a member of the insulin superfamily. It was originally discovered as a mediator of growth hormone actions on somatic cell growth, but has also been shown to be an important regulator of cell metabolism, differentiation and survival. IGF-I is synthesized as a preproprotein that is proteolytically cleaved to generate the mature protein linked by three disulfide bonds.
Mature IGF-I is highly conserved among mammals, with 100% sequence identity between the Porcine, bovine, porcine, equine and canine proteins. IGF-I is synthesized in the liver and multiple other tissues. It is found in blood and other body fluids as a complex with specific high affinity IGF binding proteins (IGFBP-1to-6).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Hu01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Hu01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Hu01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Hu01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Hu01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Mu01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Mu01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Mu01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Mu01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Mu01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Ra01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Ra01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Ra01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Ra01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Ra01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Ca01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Ca01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Ca01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Ca01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Ca01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Po01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Po01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Po01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Po01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Po01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Bo01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Bo01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Bo01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Bo01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Bo01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Rb01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Rb01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Rb01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Rb01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Rb01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW657Mo01 | Recombinant Insulin Like Growth Factor 1 (IGF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW657Mo01 | Monoclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IP. |
| PAW657Mo01 | Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW657Mo01 | CLIA Kit for Insulin Like Growth Factor 1 (IGF1) | CLIA assay for Antigen Detection |
| ELW657Mo01 | ELISA Kit for Insulin Like Growth Factor 1 (IGF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Nature 306:609-611(1983) [PubMed] [Europe PMC] [Abstract]
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FEBS Lett. 195:179-184(1986) [PubMed] [Europe PMC] [Abstract]
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Nature 503:267-271(2013) [PubMed] [Europe PMC] [Abstract]
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J. Biochem. 111:529-536(1992) [PubMed] [Europe PMC] [Abstract]
"Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene."
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Erratum
Nat. Genet. 23:373-373(1999)