Macrophage Derived Chemokine (MDC)
CCL22; ABCD1; DC/B-CK; SCYA22; STCP1; Chemokine C-C-Motif Ligand 22; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 22; Stimulated T-Cell Chemotactic Protein 1
CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes.
The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Hu01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Hu01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Hu01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Hu01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Hu01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Mu01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Mu01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Mu01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Mu01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Mu01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Ra01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Ra01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Ra01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Ra01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Ra01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Ca01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Ca01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Ca01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Ca01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Ca01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Po01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Po01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Po01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Po01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Po01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Bo01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Bo01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Bo01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Bo01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Bo01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Rb01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Rb01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Rb01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Rb01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Rb01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW619Mo01 | Recombinant Macrophage Derived Chemokine (MDC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW619Mo01 | Monoclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IP. |
| PAW619Mo01 | Polyclonal Antibody to Macrophage Derived Chemokine (MDC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW619Mo01 | CLIA Kit for Macrophage Derived Chemokine (MDC) | CLIA assay for Antigen Detection |
| ELW619Mo01 | ELISA Kit for Macrophage Derived Chemokine (MDC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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J. Biol. Chem. 272:25229-25237(1997) [PubMed] [Europe PMC] [Abstract]
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Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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J. Biol. Chem. 273:1764-1768(1998) [PubMed] [Europe PMC] [Abstract]
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Eur. J. Immunol. 31:812-822(2001) [PubMed] [Europe PMC] [Abstract]