Matrix Metalloproteinase 3 (MMP3)
SL1; STMY; STMY1; STR1; Progelatinase; Stromelysin 1; Transin-1
MMP-3 is secreted from the cells as a proenzyme. The proenzyme has been shown to stimulate plasminogen activation. The N-terminal pro-domain contains the cysteine switch motif conserved in MMPs that maintains MMP-3 in the latent state. Activation of the proenzyme results in the removal of the pro-domain. MMP-3 activation can be achieved in vitro by proteases such as itself, chyrotrypsin, neutrophil elastase and plasma kallikrein, and by mercury compounds.
The resulting active enzyme consists of a catalytic domain with a zinc-binding motif conserved in metzincins. A short hinge peptide links the catalytic domain to the C-terminal hemopexin-like domain. The active MMP-3 is capable of cleaving types III, IV, IX and X collagen, aggrecan, fibronectin, laminin, IGFBP-3, serpins, and IL-1 .
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Hu01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Hu01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Hu01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Hu01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Hu01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Mu01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Mu01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Mu01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Mu01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Mu01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Ra01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Ra01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Ra01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Ra01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Ra01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Ca01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Ca01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Ca01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Ca01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Ca01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Po01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Po01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Po01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Po01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Po01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Bo01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Bo01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Bo01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Bo01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Bo01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Rb01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Rb01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Rb01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Rb01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Rb01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW609Mo01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW609Mo01 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAW609Mo01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW609Mo01 | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | CLIA assay for Antigen Detection |
| ELW609Mo01 | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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