Adrenomedullin (ADM)
AM; PAMP; Proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide
Adrenomedullin (ADM) is a peptide associated with pheochromocytoma. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma. Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. The human AM gene is localized to a single locus on Chromosome 11 with 4 exons and 3 introns.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Hu01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Hu01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Hu01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Hu01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Hu01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Mu01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Mu01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Mu01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Mu01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Mu01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Ra01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Ra01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Ra01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Ra01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Ra01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Ca01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Ca01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Ca01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Ca01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Ca01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Po01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Po01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Po01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Po01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Po01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Bo01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Bo01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Bo01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Bo01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Bo01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Rb01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Rb01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Rb01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Rb01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Rb01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW525Mo01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW525Mo01 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAW525Mo01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW525Mo01 | CLIA Kit for Adrenomedullin (ADM) | CLIA assay for Antigen Detection |
| ELW525Mo01 | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning and characterization of cDNA encoding a precursor for human adrenomedullin."
Biochem. Biophys. Res. Commun. 194:720-725(1993) [PubMed] [Europe PMC] [Abstract]
"Genomic structure of human adrenomedullin gene."
Biochem. Biophys. Res. Commun. 203:631-639(1994) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma."
Biochem. Biophys. Res. Commun. 192:553-560(1993) [PubMed] [Europe PMC] [Abstract]
"Proadrenomedullin-derived peptides."
Front. Neuroendocrinol. 19:100-127(1998) [PubMed] [Europe PMC] [Abstract]
"Structure-activity relationships of adrenomedullin in the circulation and adrenal gland."
Regul. Pept. 85:1-8(1999) [PubMed] [Europe PMC] [Abstract]
"NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth."
Biopolymers 81:295-308(2006) [PubMed] [Europe PMC] [Abstract]