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Maltase Glucoamylase, Intestinal (MGA)

MGAM; Glucan 1,4-Alpha-Glucosidase

Maltase-glucoamylase (MGA) is a brush border membrane enzyme that plays a role in the final steps of small intestinal digestion of linear regions of starch to glucose. Brush border sucrase-isomaltase (SI) serves a complementary function through digestion of branched starch linkages. Brush-border maltase-glucoamylase (MGA) activity serves as the final step of small intestinal digestion of linear regions of dietary starch to glucose.

Maltase-glucoamylase is synthesized as a single-chain polypeptide precursor, acquires N- and O-linked carbohydrates, and does not undergo intracellular or extracellular proteolytic cleavage. Maltase is an enzyme produced by the cells lining the small intestine that breaks down the disaccharide maltose. It comes under the enzyme category carbohydrase.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Hu01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Hu01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Hu01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Hu01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Hu01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Mu01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Mu01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Mu01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Mu01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Mu01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Ra01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Ra01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Ra01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Ra01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Ra01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Ca01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Ca01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Ca01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Ca01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Ca01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Po01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Po01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Po01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Po01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Po01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Bo01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Bo01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Bo01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Bo01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Bo01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Rb01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Rb01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Rb01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Rb01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Rb01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW503Mo01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW503Mo01 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
PAW503Mo01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IF.
Assay Kits CLW503Mo01 CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA assay for Antigen Detection
ELW503Mo01 ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Human small intestinal maltase-glucoamylase cDNA cloning. Homology to sucrase-isomaltase."
J. Biol. Chem. 273:3076-3081(1998) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase."
J. Biol. Chem. 263:19709-19717(1988) [PubMed] [Europe PMC] [Abstract]

"Tyrosine sulfation, a post-translational modification of microvillar enzymes in the small intestinal enterocyte."
EMBO J. 6:2891-2896(1987) [PubMed] [Europe PMC] [Abstract]

"Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity."
J. Mol. Biol. 375:782-792(2008) [PubMed] [Europe PMC] [Abstract]