GATA Binding Protein 5 (GATA5)
Transcription factor GATA-5
Transcription factor GATA-5 is is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
GATA5 Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Hu01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Hu01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Hu01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Hu01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Hu01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Mu01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Mu01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Mu01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Mu01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Mu01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Ra01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Ra01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Ra01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Ra01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Ra01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Ca01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Ca01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Ca01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Ca01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Ca01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Po01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Po01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Po01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Po01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Po01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Bo01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Bo01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Bo01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Bo01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Bo01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Rb01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Rb01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Rb01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Rb01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Rb01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW447Mo01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW447Mo01 | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
| PAW447Mo01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW447Mo01 | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA assay for Antigen Detection |
| ELW447Mo01 | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
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"Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation."
Clinics (Sao Paulo) 67:1393-1399(2012) [PubMed] [Europe PMC] [Abstract]
"Mutational spectrum of the GATA5 gene associated with familial atrial fibrillation."
Int. J. Cardiol. 157:305-307(2012) [PubMed] [Europe PMC] [Abstract]
"Rare non-synonymous variations in the transcriptional activation domains of GATA5 in bicuspid aortic valve disease."
J. Mol. Cell. Cardiol. 53:277-281(2012) [PubMed] [Europe PMC] [Abstract]
"GATA5 loss-of-function mutations underlie tetralogy of fallot."
Int. J. Med. Sci. 10:34-42(2013) [PubMed] [Europe PMC] [Abstract]
"A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation."
Int. J. Mol. Med. 31:43-50(2013) [PubMed] [Europe PMC] [Abstract]
"GATA5 loss-of-function mutation responsible for the congenital ventriculoseptal defect."
Pediatr. Cardiol. 34:504-511(2013) [PubMed] [Europe PMC] [Abstract]
"GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve."
Int. J. Mol. Med. 33:1219-1226(2014) [PubMed] [Europe PMC] [Abstract]
"Somatic GATA5 mutations in sporadic tetralogy of Fallot."
Int. J. Mol. Med. 33:1227-1235(2014) [PubMed] [Europe PMC] [Abstract]
"GATA5 loss-of-function mutation in familial dilated cardiomyopathy."
Int. J. Mol. Med. 35:763-770(2015) [PubMed] [Europe PMC] [Abstract]