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Interferon Gamma Induced Protein 10kDa (IP10)

CXCL10; C7; IFI10; INP10; SCYB10; Crg2; GIP10; Mob1; Chemokine C-X-C Motif Ligand 10; Small Inducible Cytokine Subfamily B(Cys-X-Cys)Member 10

Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (γ-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.

CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Hu01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Hu01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Hu01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Hu01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Hu01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Mu01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Mu01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Mu01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Mu01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Mu01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Ra01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Ra01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Ra01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Ra01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Ra01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Ca01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Ca01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Ca01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Ca01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Ca01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Po01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Po01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Po01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Po01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Po01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Bo01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Bo01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Bo01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Bo01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Bo01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Rb01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Rb01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Rb01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Rb01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Rb01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW431Mo01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW431Mo01 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
PAW431Mo01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits CLW431Mo01 CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA assay for Antigen Detection
ELW431Mo01 ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins."
Nature 315:672-676(1985) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8."
J. Immunol. 150:1000-1010(1993) [PubMed] [Europe PMC] [Abstract]

"Human IP-9: a keratinocyte derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)."
J. Invest. Dermatol. 112:716-722(1999) [PubMed] [Europe PMC] [Abstract]

"Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity."
Eur. J. Biochem. 268:4992-4999(2001) [PubMed] [Europe PMC] [Abstract]

"Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation."
Blood 112:2648-2656(2008) [PubMed] [Europe PMC] [Abstract]

"The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions."
Biochemistry 41:10418-10425(2002) [PubMed] [Europe PMC] [Abstract]