GATA Binding Protein 4 (GATA4)
Transcription factor GATA-4
Transcription factor GATA-4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.A fourth member of the GATA-binding family, GATA4, is expressed in adult vertebrate heart, gut epithelium, and gonads. During fetal development, GATA4 is expressed in yolk sac endoderm and cells involved in heart formation. This factor may regulate genes critical for myocardial differentiation and function, including troponin C , cardiac alpha-myosin heavy chain (MYH6), and brain-type natriuretic factor .
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Hu01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Hu01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Hu01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Hu01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Hu01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Mu01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Mu01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Mu01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Mu01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Mu01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Ra01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Ra01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Ra01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Ra01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Ra01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Ca01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Ca01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Ca01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Ca01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Ca01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Po01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Po01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Po01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Po01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Po01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Bo01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Bo01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Bo01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Bo01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Bo01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Rb01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Rb01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Rb01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Rb01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Rb01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW428Mo01 | Recombinant GATA Binding Protein 4 (GATA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW428Mo01 | Monoclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IP. |
| PAW428Mo01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW428Mo01 | CLIA Kit for GATA Binding Protein 4 (GATA4) | CLIA assay for Antigen Detection |
| ELW428Mo01 | ELISA Kit for GATA Binding Protein 4 (GATA4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Submitted (JUL-2013) to the PDB data bank
"GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5."
Nature 424:443-447(2003) [PubMed] [Europe PMC] [Abstract]
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Pediatr. Cardiol. 33:539-546(2012) [PubMed] [Europe PMC] [Abstract]