Tissue Factor Pathway Inhibitor (TFPI)
TFI; EPI; LACI; TFPI1; Lipoprotein-Associated Coagulation Inhibitor; Extrinsic pathway inhibitor
Tissue Factor Pathway Inhibitor (TFPI) circulates in plasma as a complex with LDL>HDL>>VLDV. In plasma, TFPI is found in several forms: one at 36,000 kD, one at 43,000 kD, and the various truncated forms. This size heterogeneity appears in part to be the result of the formation of mixed disulfide complexes between TFPI and apolipoprotein AII. Approximately 10% of total TFPI is carried by platelets, which release TFPI once they are activated by thrombin. Thus, at the site of a wound, where platelets aggregate, elevated levels of TFPI are present. TFPI has dual inhibitory function (against factor Xa and factor VIIa/TF). This is consistent with the presence of multiple Kunitz-type domains: (Kunitz for factor VIIa/TF and Kunitz for factor Xa interaction).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Hu01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Hu01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Hu01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Hu01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Hu01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Mu01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Mu01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Mu01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Mu01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Mu01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Ra01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Ra01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Ra01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Ra01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Ra01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Ca01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Ca01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Ca01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Ca01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Ca01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Po01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Po01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Po01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Po01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Po01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Bo01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Bo01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Bo01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Bo01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Bo01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Rb01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Rb01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Rb01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Rb01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Rb01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW409Mo01 | Recombinant Tissue Factor Pathway Inhibitor (TFPI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW409Mo01 | Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IP. |
| PAW409Mo01 | Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW409Mo01 | CLIA Kit for Tissue Factor Pathway Inhibitor (TFPI) | CLIA assay for Antigen Detection |
| ELW409Mo01 | ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Erratum
Nat. Genet. 23:373-373(1999)