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Desmoglein 3 (DSG3)

CDHF6; PVA; 130 kDa pemphigus vulgaris antigen; Cadherin family member 6

SPN W362
HGNC 3050
MGI 99499
PubMed 8601740
RGD 1592103
UniProt P32926
Wiki Desmoglein_3

  • Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune diseases of the skin which have as target antigens 2 different members of the desmoglein subfamily of the desmosomal cadherins: pemphigus vulgaris antigen (PVA) in the case of PV and desmoglein I in the case of PF. In pemphigus vulgaris, autoantibodies against PVA, a keratinocyte cell surface 130-kD glycoprotein, cause loss of cell-cell adhesion.

  • Amagai et al. used affinity-purified pemphigus vulgaris IgG to isolate cDNA, containing the entire coding sequence for PVA, from human keratinocyte expression libraries. Northern blot analysis indicated PV mRNA expression only in stratified squamous epithelia.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Hu01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Hu01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Hu01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Hu01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Hu01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Mu01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Mu01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Mu01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Mu01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Mu01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Ra01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Ra01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Ra01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Ra01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Ra01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Ca01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Ca01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Ca01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Ca01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Ca01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Po01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Po01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Po01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Po01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Po01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Bo01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Bo01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Bo01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Bo01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Bo01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Rb01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Rb01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Rb01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Rb01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Rb01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW362Mo01 Recombinant Desmoglein 3 (DSG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW362Mo01 Monoclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IP.
PAW362Mo01 Polyclonal Antibody to Desmoglein 3 (DSG3) WB; IHC; ICC; IF.
Assay Kits CLW362Mo01 CLIA Kit for Desmoglein 3 (DSG3) CLIA assay for Antigen Detection
ELW362Mo01 ELISA Kit for Desmoglein 3 (DSG3) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion."
Cell 67:869-877(1991) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 18."
Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]

"Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
J. Proteome Res. 5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

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