Inhibin Beta C (INHbC)

IHBC; INH-Bc

SPN	W360
HGNC	6068
MGI	105932
PubMed	8838799
RGD	621194
UniProt	P55103
Wiki	INHBC

This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.

Schmitt et al. (1996) cloned a cDNA for the mouse inhibin/activin beta-C gene. The mouse gene encodes a predicted 352-amino acid prepropeptide and a 116-amino acid mature protein which is 94% identical to the human sequence. Ribonuclease protein assays showed that mouse Inhbc is mainly expressed in adult liver.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Hu01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Hu01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Hu01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Hu01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Hu01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Mu01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Mu01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Mu01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Mu01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Mu01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Ra01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Ra01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Ra01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Ra01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Ra01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Ca01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Ca01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Ca01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Ca01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Ca01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Po01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Po01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Po01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Po01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Po01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Bo01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Bo01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Bo01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Bo01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Bo01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Rb01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Rb01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Rb01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Rb01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Rb01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPW360Mo01	Recombinant Inhibin Beta C (INHbC)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAW360Mo01	Monoclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IP.
Antibodies	PAW360Mo01	Polyclonal Antibody to Inhibin Beta C (INHbC)	WB; IHC; ICC; IF.
Assay Kits	CLW360Mo01	CLIA Kit for Inhibin Beta C (INHbC)	CLIA assay for Antigen Detection
Assay Kits	ELW360Mo01	ELISA Kit for Inhibin Beta C (INHbC)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Cloning of a new member of the TGF-beta family: a putative new activin beta C chain."
Biochem. Biophys. Res. Commun. 206:608-613(1995) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Inhibins, activins, and follistatins: expression of mRNAs and cellular localization in tissues from men with benign prostatic hyperplasia."
Prostate 34:34-43(1998) [PubMed] [Europe PMC] [Abstract]