Myoglobin (MYO)
PVALB; MB
Myoglobin is a single-chain globular protein of 153 amino acids, containing a heme prosthetic group in the center around which the remaining apoprotein folds. It has eight alpha helices and a hydrophobic core. It has a molecular weight of 16,700 daltons, and is the primary oxygen-carrying pigment of muscle tissues. Unlike the blood-borne hemoglobin, to which it is structurally related, this protein does not exhibit cooperative binding of oxygen, since positive cooperativity is a property of multimeric/oligomeric proteins only. Instead, the binding of oxygen by myoglobin is unaffected by the oxygen pressure in the surrounding tissue. Myoglobin is often cited as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Hu01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Hu01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Hu01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Hu01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Hu01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Mu01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Mu01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Mu01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Mu01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Mu01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Ra01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Ra01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Ra01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Ra01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Ra01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Ca01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Ca01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Ca01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Ca01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Ca01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Po01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Po01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Po01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Po01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Po01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Bo01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Bo01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Bo01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Bo01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Bo01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Rb01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Rb01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Rb01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Rb01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Rb01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW326Mo01 | Recombinant Myoglobin (MYO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW326Mo01 | Monoclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IP. |
PAW326Mo01 | Polyclonal Antibody to Myoglobin (MYO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW326Mo01 | CLIA Kit for Myoglobin (MYO) | CLIA assay for Antigen Detection |
ELW326Mo01 | ELISA Kit for Myoglobin (MYO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Organization of the human myoglobin gene."
EMBO J. 3:439-446(1984) [PubMed] [Europe PMC] [Abstract]
"Cloning of the human myoglobin gene."
Gene 33:241-249(1985) [PubMed] [Europe PMC] [Abstract]
"A genome annotation-driven approach to cloning the human ORFeome."
Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Primary structure of human myoglobin."
Nature New Biol. 232:149-152(1971) [PubMed] [Europe PMC] [Abstract]
"The myoglobin of primates. I. Hylobates agilis (gibbon)."
Biochim. Biophys. Acta 251:482-488(1971) [PubMed] [Europe PMC] [Abstract]
"The myoglobin of primates. II. Pan troglodytes (chimpanzee)."
Biochim. Biophys. Acta 278:62-67(1972) [PubMed] [Europe PMC] [Abstract]
"The human myocardial two-dimensional gel protein database: update 1994."
Electrophoresis 15:1459-1465(1994) [PubMed] [Europe PMC] [Abstract]
"Abnormal human myoglobin: 53 (D4) glutamic acid-->lysine."
Nature 223:832-833(1969) [PubMed] [Europe PMC] [Abstract]
"The third variant of human myoglobin showing an unusual amino acid substitution: 138(H16)arginine-->tryptophan."
Biochim. Biophys. Acta 229:716-719(1971) [PubMed] [Europe PMC] [Abstract]
"A human myoglobin variant 133 (H-10)lysine-->asparagine."
Biochim. Biophys. Acta 229:871-876(1971) [PubMed] [Europe PMC] [Abstract]
"The second variant of human myoglobin; 138(H16) arginine leads to glutamine."
Br. J. Haematol. 20:69-74(1971) [PubMed] [Europe PMC] [Abstract]
"X-ray crystal structure of a recombinant human myoglobin mutant at 2.8-A resolution."
J. Mol. Biol. 213:215-218(1990) [PubMed] [Europe PMC] [Abstract]