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Myoglobin (MYO)

PVALB; MB

Myoglobin is a single-chain globular protein of 153 amino acids, containing a heme prosthetic group in the center around which the remaining apoprotein folds. It has eight alpha helices and a hydrophobic core. It has a molecular weight of 16,700 daltons, and is the primary oxygen-carrying pigment of muscle tissues. Unlike the blood-borne hemoglobin, to which it is structurally related, this protein does not exhibit cooperative binding of oxygen, since positive cooperativity is a property of multimeric/oligomeric proteins only. Instead, the binding of oxygen by myoglobin is unaffected by the oxygen pressure in the surrounding tissue. Myoglobin is often cited as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Hu01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Hu01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Hu01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Hu01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Hu01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Mu01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Mu01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Mu01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Mu01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Mu01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Ra01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Ra01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Ra01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Ra01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Ra01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Ca01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Ca01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Ca01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Ca01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Ca01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Po01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Po01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Po01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Po01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Po01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Bo01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Bo01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Bo01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Bo01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Bo01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Rb01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Rb01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Rb01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Rb01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Rb01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW326Mo01 Recombinant Myoglobin (MYO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW326Mo01 Monoclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IP.
PAW326Mo01 Polyclonal Antibody to Myoglobin (MYO) WB; IHC; ICC; IF.
Assay Kits CLW326Mo01 CLIA Kit for Myoglobin (MYO) CLIA assay for Antigen Detection
ELW326Mo01 ELISA Kit for Myoglobin (MYO) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Organization of the human myoglobin gene."
EMBO J. 3:439-446(1984) [PubMed] [Europe PMC] [Abstract]

"Cloning of the human myoglobin gene."
Gene 33:241-249(1985) [PubMed] [Europe PMC] [Abstract]

"A genome annotation-driven approach to cloning the human ORFeome."
Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Primary structure of human myoglobin."
Nature New Biol. 232:149-152(1971) [PubMed] [Europe PMC] [Abstract]

"The myoglobin of primates. I. Hylobates agilis (gibbon)."
Biochim. Biophys. Acta 251:482-488(1971) [PubMed] [Europe PMC] [Abstract]

"The myoglobin of primates. II. Pan troglodytes (chimpanzee)."
Biochim. Biophys. Acta 278:62-67(1972) [PubMed] [Europe PMC] [Abstract]

"The human myocardial two-dimensional gel protein database: update 1994."
Electrophoresis 15:1459-1465(1994) [PubMed] [Europe PMC] [Abstract]

"Abnormal human myoglobin: 53 (D4) glutamic acid-->lysine."
Nature 223:832-833(1969) [PubMed] [Europe PMC] [Abstract]

"The third variant of human myoglobin showing an unusual amino acid substitution: 138(H16)arginine-->tryptophan."
Biochim. Biophys. Acta 229:716-719(1971) [PubMed] [Europe PMC] [Abstract]

"A human myoglobin variant 133 (H-10)lysine-->asparagine."
Biochim. Biophys. Acta 229:871-876(1971) [PubMed] [Europe PMC] [Abstract]

"The second variant of human myoglobin; 138(H16) arginine leads to glutamine."
Br. J. Haematol. 20:69-74(1971) [PubMed] [Europe PMC] [Abstract]

"X-ray crystal structure of a recombinant human myoglobin mutant at 2.8-A resolution."
J. Mol. Biol. 213:215-218(1990) [PubMed] [Europe PMC] [Abstract]