Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1)
MOX1; GP91-2; NOH1; NADPH Oxidase 1; Mitogenic Oxidase(Pyridine Nucleotide-Dependent Superoxide-Generating; NADH/NADPH mitogenic oxidase subunit P65-MOX
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.By searching EST databases for sequences with homology to gp91-phox, Suh et al. (1999) identified the NOH1 gene, which they called MOX1. MOX1 was expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Hu01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Hu01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Hu01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Hu01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Hu01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Mu01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Mu01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Mu01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Mu01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Mu01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Ra01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Ra01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Ra01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Ra01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Ra01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Ca01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Ca01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Ca01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Ca01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Ca01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Po01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Po01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Po01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Po01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Po01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Bo01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Bo01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Bo01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Bo01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Bo01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Rb01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Rb01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Rb01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Rb01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Rb01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW256Mo01 | Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW256Mo01 | Monoclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IP. |
| PAW256Mo01 | Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW256Mo01 | CLIA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | CLIA assay for Antigen Detection |
| ELW256Mo01 | ELISA Kit for Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cell transformation by the superoxide-generating oxidase Mox1."
Nature 401:79-82(1999) [PubMed] [Europe PMC] [Abstract]
"A mammalian H+ channel, generated through alternative splicing of the NADPH oxidase homolog NOH-1."
Science 287:138-142(2000) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain."
J. Biol. Chem. 279:4737-4742(2004) [PubMed] [Europe PMC] [Abstract]
"Molecular interaction of NADPH oxidase 1 with betaPix and Nox Organizer 1."
Biochem. Biophys. Res. Commun. 339:985-990(2006) [PubMed] [Europe PMC] [Abstract]
"Nox1-dependent reactive oxygen generation is regulated by Rac1."
J. Biol. Chem. 281:17718-17726(2006) [PubMed] [Europe PMC] [Abstract]
"Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity."
Sci. Signal. 2:RA54-RA54(2009) [PubMed] [Europe PMC] [Abstract]
"N-Linked glycosylation of the superoxide-producing NADPH oxidase Nox1."
Biochem. Biophys. Res. Commun. 443:1060-1065(2014) [PubMed] [Europe PMC] [Abstract]