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Cytochrome C, Somatic (CYCS)

Cyt-C; HCS; CYC; CytC

Cytochrome c, or cyt c (horse heart: PDB 1HRC) is a small heme protein found loosely associated with the inner membrane of the mitochondrion. It is a soluble protein, unlike other cytochromes, and is an essential component of the electron transfer chain. It is capable of undergoing oxidation and reduction, but does not bind oxygen. It transfers electrons between Complexes III and IV.
Cytochrome c is a highly conserved protein across the spectrum of species, found in plants, animals, and many unicellular organisms. This, along with its small size (molecular weight about 12,000 daltons), makes it useful in studies of evolutionary divergence. Its primary structure consists of a chain of 100 amino acids.
 

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Hu01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Hu01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Hu01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Hu01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Hu01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Mu01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Mu01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Mu01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Mu01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Mu01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Ra01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Ra01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Ra01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Ra01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Ra01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Ca01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Ca01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Ca01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Ca01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Ca01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Po01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Po01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Po01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Po01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Po01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Bo01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Bo01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Bo01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Bo01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Bo01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Rb01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Rb01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Rb01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Rb01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Rb01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW216Mo01 Recombinant Cytochrome C, Somatic (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW216Mo01 Monoclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IP.
PAW216Mo01 Polyclonal Antibody to Cytochrome C, Somatic (CYCS) WB; IHC; ICC; IF.
Assay Kits CLW216Mo01 CLIA Kit for Cytochrome C, Somatic (CYCS) CLIA assay for Antigen Detection
ELW216Mo01 ELISA Kit for Cytochrome C, Somatic (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"The human somatic cytochrome c gene: two classes of processed pseudogenes demarcate a period of rapid molecular evolution."
Proc. Natl. Acad. Sci. U.S.A. 85:9625-9629(1988) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 7: DNA sequence and biology."
Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The amino acid sequence of human heart cytochrome c."
J. Biol. Chem. 237:3575-3576(1962) [PubMed] [Europe PMC] [Abstract]

"Human heart cytochrome c. Chymotryptic peptides, tryptic peptides, and the complete amino acid sequence."
J. Biol. Chem. 238:2732-2753(1963) [PubMed] [Europe PMC] [Abstract]

"Cytochrome c in the apoptotic and antioxidant cascades."
FEBS Lett. 423:275-280(1998) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Solution structure of reduced recombinant human cytochrome c."
Submitted (FEB-2003) to the PDB data bank

"A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia."
Nat. Genet. 40:387-389(2008) [PubMed] [Europe PMC] [Abstract]