Peroxisomal Biogenesis Factor 2 (PEX2)
PXMP3; PAF1; PMP35; PMP3; RNF72; Peroxin 2; Peroxisome Assembly Factor 1; Peroxisomal Membrane Protein 35kDa; Peroxisomal Membrane Protein 3
Peroxisome assembly factor 1 is a protein encodes an integral peroxisomal membrane protein required for peroxisome biogenesis. The protein is thought to be involved in peroxisomal matrix protein import. Mutations in this gene result in one form of Zellweger syndrome and infantile Refsum disease. Alternative splicing results in multiple transcript variants encoding the same protein.Shimozawa et al. (1992) demonstrated a point mutation in peroxisome assembly factor-1 (PAF1), a 35-kD peroxisomal membrane protein (PMP35) for which the cDNA had been cloned by Tsukamoto et al. (1991). They had previously shown that this protein corrected the Zellweger-like defect in peroxisome assembly in a peroxisome-deficient Chinese hamster ovary mutant cell line (Z65).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Hu01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Hu01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Hu01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Hu01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Hu01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Mu01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Mu01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Mu01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Mu01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Mu01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Ra01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Ra01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Ra01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Ra01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Ra01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Ca01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Ca01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Ca01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Ca01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Ca01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Po01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Po01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Po01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Po01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Po01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Bo01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Bo01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Bo01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Bo01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Bo01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Rb01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Rb01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Rb01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Rb01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Rb01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW208Mo01 | Recombinant Peroxisomal Biogenesis Factor 2 (PEX2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW208Mo01 | Monoclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IP. |
| PAW208Mo01 | Polyclonal Antibody to Peroxisomal Biogenesis Factor 2 (PEX2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW208Mo01 | CLIA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | CLIA assay for Antigen Detection |
| ELW208Mo01 | ELISA Kit for Peroxisomal Biogenesis Factor 2 (PEX2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A human gene responsible for Zellweger syndrome that affects peroxisome assembly."
Science 255:1132-1134(1992) [PubMed] [Europe PMC] [Abstract]
"Genomic organization and characterization of human PEX2 encoding a 35-kDa peroxisomal membrane protein."
Biochem. Biophys. Res. Commun. 273:985-990(2000) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Ring finger in the peroxisome assembly factor-1."
FEBS Lett. 312:1-2(1992) [PubMed] [Europe PMC] [Abstract]
"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
"Defective PEX gene products correlate with the protein import, biochemical abnormalities, and phenotypic heterogeneity in peroxisome biogenesis disorders."
J. Med. Genet. 36:779-781(1999) [PubMed] [Europe PMC] [Abstract]