Caspase 3 (CASP3)
CPP32; CPP32B; SCA1; Apoptain; Yama; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 3; SREBP cleavage activity 1
Caspase-3 (CPP-32, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position (2).a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Hu01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Hu01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Hu01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Hu01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Hu01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Mu01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Mu01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Mu01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Mu01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Mu01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Ra01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Ra01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Ra01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Ra01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Ra01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Ca01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Ca01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Ca01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Ca01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Ca01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Po01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Po01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Po01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Po01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Po01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Bo01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Bo01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Bo01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Bo01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Bo01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Rb01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Rb01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Rb01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Rb01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Rb01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW185Mo01 | Recombinant Caspase 3 (CASP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW185Mo01 | Monoclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IP. |
| PAW185Mo01 | Polyclonal Antibody to Caspase 3 (CASP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW185Mo01 | CLIA Kit for Caspase 3 (CASP3) | CLIA assay for Antigen Detection |
| ELW185Mo01 | ELISA Kit for Caspase 3 (CASP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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