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Fibroblast Growth Factor 7 (FGF7)

KGF; HBGF7; Keratinocyte Growth Factor; Heparin-binding growth factor 7

Keratinocyte growth factor is a protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.

Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Hu01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Hu01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Hu01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Hu01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Hu01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Mu01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Mu01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Mu01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Mu01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Mu01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Ra01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Ra01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Ra01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Ra01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Ra01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Ca01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Ca01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Ca01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Ca01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Ca01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Po01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Po01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Po01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Po01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Po01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Bo01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Bo01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Bo01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Bo01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Bo01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Rb01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Rb01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Rb01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Rb01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Rb01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW175Mo01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW175Mo01 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAW175Mo01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IF.
Assay Kits CLW175Mo01 CLIA Kit for Fibroblast Growth Factor 7 (FGF7) CLIA assay for Antigen Detection
ELW175Mo01 ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth."
Science 245:752-755(1989) [PubMed] [Europe PMC] [Abstract]

"Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity."
Ann. N. Y. Acad. Sci. 638:62-77(1991) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Analysis of the DNA sequence and duplication history of human chromosome 15."
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Purification and characterization of a newly identified growth factor specific for epithelial cells."
Proc. Natl. Acad. Sci. U.S.A. 86:802-806(1989) [PubMed] [Europe PMC] [Abstract]

"Receptor specificity of the fibroblast growth factor family."
J. Biol. Chem. 271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]

"The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair."
Oncogene 24:5269-5277(2005) [PubMed] [Europe PMC] [Abstract]

"Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family."
J. Biol. Chem. 281:15694-15700(2006) [PubMed] [Europe PMC] [Abstract]

"Fibroblast growth factor signalling: from development to cancer."
Nat. Rev. Cancer 10:116-129(2010) [PubMed] [Europe PMC] [Abstract]