Hexosaminidase B Beta (HEXb)
Hex-B; ENC-1AS; HCC-7; Beta-N-acetylhexosaminidase subunit beta; Cervical cancer proto-oncogene 7 protein; N-acetyl-beta-glucosaminidase subunit beta
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.
Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Hu01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Hu01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Hu01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Hu01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Hu01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Mu01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Mu01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Mu01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Mu01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Mu01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Ra01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Ra01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Ra01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Ra01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Ra01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Ca01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Ca01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Ca01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Ca01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Ca01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Po01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Po01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Po01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Po01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Po01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Bo01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Bo01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Bo01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Bo01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Bo01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Rb01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Rb01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Rb01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Rb01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Rb01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW174Mo01 | Recombinant Hexosaminidase B Beta (HEXb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW174Mo01 | Monoclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IP. |
| PAW174Mo01 | Polyclonal Antibody to Hexosaminidase B Beta (HEXb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW174Mo01 | CLIA Kit for Hexosaminidase B Beta (HEXb) | CLIA assay for Antigen Detection |
| ELW174Mo01 | ELISA Kit for Hexosaminidase B Beta (HEXb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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