Glutathione S Transferase Alpha 3 (GSTa3)
GST-A3; GSTA3-3; GTA3; GST class-alpha member 3
By searching a genomic sequence database with the GSTA1 and GSTA4 sequences, Morel et al. (2002) identified 1 BAC and 3 PAC clones covering more than 400 kb and containing the entire GST-alpha gene cluster. The cluster consists of 5 genes, GSTA1, GSTA2, GSTA3, GSTA4, and GSTA5, as well as 7 pseudogenes. The deduced GSTA3 protein contains 222 amino acids. By RT-PCR using gene-specific probes, Morel et al. (2002) demonstrated that GSTA1, GSTA2, and GSTA4 transcripts are widely expressed in human tissues, whereas the GSTA3 transcript appears to be a rare message subject to splicing defects. Although GSTA5 appears to be a functional gene, expression of GSTA5 could not be detected in any tissues examined.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Hu01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Hu01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Hu01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Hu01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Hu01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Mu01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Mu01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Mu01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Mu01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Mu01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Ra01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Ra01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Ra01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Ra01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Ra01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Ca01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Ca01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Ca01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Ca01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Ca01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Po01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Po01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Po01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Po01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Po01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Bo01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Bo01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Bo01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Bo01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Bo01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Rb01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Rb01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Rb01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Rb01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Rb01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW141Mo01 | Recombinant Glutathione S Transferase Alpha 3 (GSTa3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW141Mo01 | Monoclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IP. |
| PAW141Mo01 | Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW141Mo01 | CLIA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | CLIA assay for Antigen Detection |
| ELW141Mo01 | ELISA Kit for Glutathione S Transferase Alpha 3 (GSTa3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Genomics 18:680-686(1993) [PubMed] [Europe PMC] [Abstract]
"Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones."
J. Biol. Chem. 276:33061-33065(2001) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4."
Biochem. J. 330:827-831(1998) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity."
Biochemistry 43:15673-15679(2004) [PubMed] [Europe PMC] [Abstract]
"Structural basis for featuring of steroid isomerase activity in alpha class glutathione transferases."
J. Mol. Biol. 397:332-340(2010) [PubMed] [Europe PMC] [Abstract]