Toll Like Receptor 9 (TLR9)
CD289
- Toll-like receptors (TLRs) recognize microbial products and initiate a complex immune response designed to eliminate invading pathogens.
- TLR9 is specialized to recognize microbial nucleic acids, and 1 factor enabling TLR9 to discriminate between self and foreign DNA is the presence of unmethylated CpG dinucleotides in bacterial DNA (Hasan et al., 2007).other TLR proteins, TLR9 contains extracellular leucine-rich repeats (LRRs) and a cytoplasmic toll/interleukin-1R (TIR) domain. It also has a signal peptide (residues 1 to 25) and a transmembrane domain (residues 819 to 836). Northern blot analysis of mouse tissues revealed highest Tlr9 expression in spleen.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Hu01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Hu01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Hu01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Hu01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Hu01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Mu01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Mu01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Mu01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Mu01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Mu01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Ra01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Ra01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Ra01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Ra01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Ra01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Ca01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Ca01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Ca01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Ca01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Ca01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Po01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Po01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Po01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Po01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Po01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Bo01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Bo01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Bo01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Bo01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Bo01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Rb01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Rb01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Rb01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Rb01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Rb01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW103Mo01 | Recombinant Toll Like Receptor 9 (TLR9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW103Mo01 | Monoclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IP. |
| PAW103Mo01 | Polyclonal Antibody to Toll Like Receptor 9 (TLR9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW103Mo01 | CLIA Kit for Toll Like Receptor 9 (TLR9) | CLIA assay for Antigen Detection |
| ELW103Mo01 | ELISA Kit for Toll Like Receptor 9 (TLR9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Three novel mammalian Toll-like receptors: gene structure, expression, and evolution."
Eur. Cytokine Netw. 11:362-371(2000) [PubMed] [Europe PMC] [Abstract]
"Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9."
Eur. Cytokine Netw. 11:372-378(2000) [PubMed] [Europe PMC] [Abstract]
"A Toll-like receptor recognizes bacterial DNA."
Nature 408:740-745(2000) [PubMed] [Europe PMC] [Abstract]
"Natural selection in the TLR-related genes in the course of primate evolution."
Immunogenetics 60:727-735(2008) [PubMed] [Europe PMC] [Abstract]
"The heterogeneous allelic repertoire of human Toll-Like receptor (TLR) genes."
PLoS ONE 4:E7803-E7803(2009) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells."
J. Immunol. 167:3555-3558(2001) [PubMed] [Europe PMC] [Abstract]
"Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase."
J. Biol. Chem. 282:36953-36960(2007) [PubMed] [Europe PMC] [Abstract]
"Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone."
Nat. Commun. 1:79-79(2010) [PubMed] [Europe PMC] [Abstract]
Erratum
Nat. Commun. 3:653-653(2012)
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]